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Chemical proteomic analysis of alk-baicalein labeled proteins in S. Typhimurium. (A) Alkyne-flavonoid probes for activity-based protein profiling studies. (B) Effect of alkyne-flavonoid probes on the levels of SPI-1 T3SS secreted proteins in S. Typhimurium culture growth media. (C) In-gel fluorescence analysis of alkyne-flavonoid probe labeling of S. Typhimurium proteins following click chemistry reaction with az-rho fluorescence dye.
