Table 5.
Tumor weight and IRw in H22 tumor-bearing mice after H22 cells injected at day 0 (2 mg/kg per day, administered on days 1–9, killed and measured on day 10, n=10)
| Group | Tumor weight (g) | IRw (%) |
|---|---|---|
| PBS | 1.46±0.21 | – |
| DM-NCTD | 1.02±0.3 | 30.14 |
| DM-NCTD/PEG liposomes | 0.87±0.1* | 40.41 |
| DM-NCTD/FA-PEG liposomes | 0.47±0.16**,## | 67.81 |
Notes:
**
P<0.01,
*
P<0.05 vs DM-NCTD group;
##
P<0.01 vs DM-NCTD/PEG liposome group. Data presented as mean ± standard deviation.
Abbreviations: IRw, inhibition rate on tumor weight; PBS, phosphate-buffered saline; DM, diacid metabolite; NCTD, norcantharidin; PEG, polyethylene glycol; FA, folic acid.