TABLE 1.
Demographic characteristics of study population
| Characteristic | Diabetes n = 233 |
Chronic HTN n = 387 |
Multiple gestation n = 315 |
Previous preeclampsia n = 323 |
P valuea |
|---|---|---|---|---|---|
| Maternal age at randomization, mean ± SD |
26.0 (6.04) | 29.5 (6.48) | 25.0 (5.88) | 24.4 (5.40) | <.001 |
| Race, n (%) | |||||
| White | 139 (59.66) | 96 (24.81) | 109 (34.60) | 71 (21.98) | <.001 |
| Hispanic | 15 (6.44) | 36 (9.30) | 37 (11.75) | 8 (2.48) | |
| African American | 77 (33.05) | 254 (65.63) | 168 (53.33) | 244 (75.54) | |
| Other | 2 (0.86) | 1 (0.26) | 1 (0.32) | 0 (0.00) | |
| Parity (deliveries >20 wks), mean ± SD |
0.82 (1.20) | 1.62 (1.60) | 1.11 (1.21) | 1.77 (1.14) | <.001 |
| Body mass index (kg/m2), geometric mean (95% CI) |
27.1 (26.23–27.96) | 31.9 (31.08–32.78) | 25.7 (24.99–26.36) | 27.4 (26.57–28.16) | <.001 |
| Gestational age at enrollment (wks), mean ± SD |
18.0 (3.69) | 19.8 (3.79) | 21.1 (3.60) | 20.0 (3.96) | <.001 |
| Gestational age at delivery (wks), mean ± SD |
36.0 (4.10) | 36.9 (3.97) | 34.4 (3.59) | 37.5 (3.63) | <.001 |
| Infant death, n (%) | 1 (0.43) | 3 (0.78) | 9 (2.86) | 3 (0.93) | .06 |
| Maternal death, n (%) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (0.17) | .69 |
CI, confidence interval; HTN, hypertension.
a
Comparisons between groups were made using analysis of variance for continuous variables, χ2 tests for categorical measures, and Fisher exact test for infant and maternal death.
Metz. Preeclampsia biomarkers in high-risk groups. Am J Obstet Gynecol 2014.