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Pharmacokinetic parameters of MeIQx following a single oral administration of 21 μg 14C-MeIQx to humans
| Subject | T1/2 elim. (hr) |
Tmax (hr) |
Cmax (ng/ml) |
AUC0–t (ng-hr/ml) |
Vd (ml) |
Cl (ml/hr) |
|---|---|---|---|---|---|---|
| C1 | 3.9 | 1.0 | 0.59 | 1.5 | 63844 | 13762 |
| C2 | 3.2 | 1.0 | 0.31 | 0.9 | 97495 | 24062 |
| C3 | 7.5 | 1.0 | 0.55 | 1.3 | 119585 | 16052 |
| C4 | 3.2 | 1.0 | 0.80 | 2.6 | 31476 | 7933 |
| P1 | 3.4 | 1.0 | 0.53 | 1.6 | 55194 | 13301 |
| P4 | 4.0 | 0.5 | 0.91 | 2.6 | 36370 | 7933 |
