Table 1. List of mutations detected in sequenced clones that define phenotypes 1, 2, 3 and 4 (see Fig 2).
Clone | Mutations | ||||||
---|---|---|---|---|---|---|---|
1 | YrfF G99V | ||||||
Phenotype 1 | 2 | YrfF G99V | |||||
(Mucoid, Day 6) | 3 | YrfF G99V | |||||
4 | YrfF G99V | ||||||
1 | YrfF Y98D | Wzc D642G | MenB M56I | IS2 ompT/pauD | IS5 htrL/rfaD | YcgE E71V | |
Phenotype 2 | 2 | YrfF Y98D | Wzc D642G | IS2 ompT/pauD | IS5 htrL/rfaD | ||
(Mucoid, Day 15) | 3 | YrfF Y98D | Wzc D642G | MenB M56I | IS2 ompT/pauD | IS5 htrL/rfaD | |
4 | YrfF Y98D | Wzc D642G | MenB M56I | IS2 ompT/pauD | IS5 htrL/rfaD | ||
1 | IS5 csrA/alaS | FrcK V211V | |||||
Phenotype 3 | 2 | IS5 csrA/alaS | ynfF +T(981/2424bp) | ||||
(Day 30) | 3 | IS5 csrA/alaS | |||||
4 | IS5 csrA/alaS | ||||||
1 | mglC (138bp) | ||||||
Phenotype 4 | 2 | IS5 mglC | |||||
(Day 30) | 3 | IS1 mgl C | |||||
4 | BarA D472N |
Genes and amino acid sequence modifications are given for the SNPs. Mutations due to insertion sequences (IS) are described by the IS number and insertion position.