Table 3. Sources of heterogeneity in MF ILC differentially expressed genes.
| Gene | HET.P | HET.F | HET.IT | pval.P | pval.F |
|---|---|---|---|---|---|
| LAMB3 | 46.2 | 41.7 | 12.1 | 0.11 | 1.05E-09 |
| CDH1 | 0.0 | 73.8 | 26.2 | 1.00 | 3.16E-09 |
| SPRY2 | 0.0 | 75.1 | 24.9 | 1.00 | 3.42E-09 |
| NTRK2 | 0.0 | 65.5 | 34.5 | 1.00 | 1.19E-06 |
| FIGF | 1.5 | 62.0 | 36.5 | 1.00 | 4.56E-06 |
| SFRP1 | 5.5 | 54.9 | 39.6 | 1.00 | 4.82E-05 |
| KIT | 8.6 | 47.1 | 44.3 | 0.86 | 3.82E-04 |
| RELN | 15.1 | 42.4 | 42.6 | 0.69 | 7.53E-04 |
| MMP7 | 19.1 | 26.1 | 54.8 | 0.39 | 0.04 |
| PROM1 | 54.3 | 5.5 | 40.2 | 0.01 | 0.44 |
HET.P, variability between tumors in different patients, expressed as a percentage of total variability from: multiple punches in each tumor, variability between foci within patients and variability between tumors in different patients. pval.P, corresponding p-value for heterogeneity between tumors in different patients. HET.F, variability between foci within patients, expressed as a percentage of total variability. pval.F, corresponding p-value for heterogeneity between foci within patients. HET.IT, variability within tumors (intra-tumor heterogeneity) expressed as a percentage of total variability.