Fig 4. Plasma NEFA concentrations are reduced after oleic acid treatment in septic animals.
Mice were treated for 14 days with oleic acid. On the 15th day, mice were subjected to CLP. Twenty-four hours after CLP, blood was collected for albumin quantification. (A)Total NEFA concentration (sum of average concentrations of the five NEFA) 24 hours after CLP in OA-treated and untreated animals. (B) Plasma concentrations of palmitoleic, linoleic, palmitic, oleic and stearic acids. (C) Plasma albumin levels. (D) Ratio of serum NEFA and albumin. Values represent the mean ± SEM of at least 5 animals. (Total NEFA and single fatty acid: sham = 7 animals, sham + OA = 5 animals, CLP = 6 animals and CLP + OA = 8 animals; Albumin and ratio of serum NEFA and albumin: sham = 5 animals, sham + OA = 6 animals, CLP = 5 animals and CLP + OA = 6 animals). The results are representative of 3 independent experiments. p < 0.05 * CLP vs sham, # CLP vs CLP plus oleic acid.