Fig 6. Oleic acid treatment decreases MDA formation, and induces UCP2 and AMPK in septic mice.
Mice were treated for 14 days with oleic acid, and on the 15th day, CLP was performed. The liver was removed 24 hours after CLP for analysis of (A) MDA and (B) UCP2 by western blotting. The graph shows the densitometric analysis of the UCP2, AMPK and β-actin bands, as described in the methods. The results are expressed as the mean ± SEM of 5–6 animals. (* and +) p < 0.05 compared to sham and sham + OA (respectively) and (#) compared to CLP.