Table.
Cumulative incidence (n) |
Baselineyear* | 2011 compared to baselineyear |
|||||||
---|---|---|---|---|---|---|---|---|---|
2007 | 2008 | 2009 | 2010 | 2011 | CIR (95%CI) | p value | Relative risk reduction† | ||
Age (years) | |||||||||
<1 | 26.9 (167) | 14.4 (92) | 6.3 (42) | 4.4 (30) | 2.0 (14) | 2010 | 0.46 (0.24–0.86) | 0.02 | 54% |
1–4 | 30.6 (652) | 14.2 (312) | 3.6 (83) | 6.0 (140) | 1.5 (37) | 2009 | 0.43 (0.29–0.63) | <0.0001 | 57% |
5–4 | 32.6 (1339) | 15.3 (649) | 5.5 (243) | 10.9 (492) | 2.0 (92) | 2009 | 0.36 (0.29–0.46) | <0.0001 | 64% |
15–29 | 11.6 (417) | 5.3 (195) | 1.9 (72) | 1.8 (71) | 0.7 (28) | 2010 | 0.39 (0.25–0.6) | <0.0001 | 61% |
≥30 | 4.8 (185) | 3.3 (132) | 0.7 (30) | 0.6 (24) | 0.3 (11) | 2010 | 0.45 (0.22–0.91) | 0.003 | 55% |
Total (1–29) | 24.4 (2408) | 11.4 (1156) | 3.8 (398) | 6.5 (703) | 1.4 (157) | 2009 | 0.38 (0.31–0.45) | <0.0001 | 62% |
Total (<1, ≥30) | 7.8 (352) | 4.8 (224) | 1.5 (72) | 1.1 (54) | 0.5 (25) | 2010 | 0.45 (0.28–0.73) | 0.001 | 55% |
CIR=cumulative incidence ratio.
The year with the lowest incidence before implementation was used as the baseline year for comparison to 2011.
Relative risk reduction indicates a decrease in risk of meningitis in the aff ected population relative to the baseline after vaccine introduction calculated as (1–CIR)×100.