Table 3. Diagnostic value of CEA and KRAS to differentiate mucinous vs. non-mucinous cysts.

	All patients n = 943			Surgical cohort n = 147			Clinical cohort n = 796
Test	KRAS+	CEA↑	KRAS+ or CEA↑	KRAS+	CEA↑	KRAS+ or CEA↑	KRAS+	CEA↑	KRAS+ or CEA↑
Sensitivity %	48.3	56.3	75.8	46.3	63.2	77	48.8	54.6	75.6
Specificity %	100	93.2	93.2	100	90.9	91.1	100	93.8	93.8
PPV %	100	95.4	96.6	100	94.8	95.7	100	95.6	96.8
NPV %	47	45.9	60.6	40.2	48.3	60.7	48.2	45.2	60.5
Accuracy %	64.5	66.8	80.9*	60.5	70.8	81.6^	65.3	65.8	80.81
AUC	0.742	0.748	0.846*	0.730	0.781	0.838~	0.744	0.742	0.8471

Abbreviation: PPV, positive predictive value; NPV, negative predictive value; AUC, area under curve

¹ P < 0.0001 vs. KRAS + and CEA↑ alone, ^P < 0.01 vs KRAS + , > 0.05 vs CEA↑ alone,^~ P > 0.05 vs. KRAS + and CEA↑ alone