Table 1. Significant Differences in Brain Activation of the Repeated-Measurement Analyses with the Factor ‘Dopamine', ‘Task' and ‘Food'.

Effect	Brain region	MNI coordinates			Cluster size (in voxels)a	T-value
		x	y	z
Main ‘dopamine': DOPD<CON	Caudate (head)	6	11	−2	7	3.99b
	Caudate (body)	12	5	16	10	3.76b
Main ‘dopamine': DOPD>CON	Superior frontal gyrus	18	47	31	23	4.84
Main ‘task': W>L	Parahippocampus/hippocampus/amygdala/putamen/fusiform gyrus	−24	−37	−11	603	5.58
	Anterior/middle cingulate cortex	−3	17	37	128	5.63
	Parahippocampus/hippocampus/amygdala/putamen/fusiform gyrus	30	−28	−11	615	5.41
	Ventromedial prefrontal cortex	0	47	−8	276	4.88
Dopamine × task	Hippocampus	−30	−25	−11	15	5.09
Dopamine × BMI (CON>DOPD)	Supplementary motor region/postcentral cortex	−18	−7	64	306	5.77
	Superior temporal cortex	48	−22	−5	16	5.56
	Anterior cingulate cortex	−6	44	4	101	5.54

Abbreviations: CON, control; DOPD, dopamine depletion; L, liking; W, wanting.

All results are family-wise error-corrected for multiple comparison.

^aThe cluster size of FWE-corrected clusters, based on a primary uncorrected-threshold level of P<0.001.

^bROI analyses, results are significant with P<0.05 at cluster and peak level.