Table 1. Experimental Groups and Design.

Figure	Manipulation	Treatment	Regimen	Assays performed	Other assays
1	Amygdala infusion	Mecamylamine (1 ng @ 2 μg/ml)	Acute (30 min before test)	Tail suspension
2, 3	β2 amygdala knockdown		Chronic (~5 weeks before test)	Light/dark, tail suspension, forced swim, social defeat	c-fos, locomotion
	α7 amygdala knockdown
4	Amygdala knockdown (β2 or α7)	Mecamylamine (1 mg/kg)	Acute (30 min before each test)	Tail suspension, social defeat	Locomotion
5	Amygdala knockdown (β2 or α7)	Physostigmine (0.15 mg/kg)	Acute (60 min before test)	Tail suspension, forced swim	Locomotion