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Trend-estimated odds ratios (ORs) for colorectal adenoma for a 20-mg/dL increase in low-density lipoprotein cholesterol concentration, Asia, 2000–2014. Squares represent study-specific estimates and are proportional in size to the weight from random-effects meta-analysis (larger squares indicate more weight). For the overall estimate from random-effects meta-analysis, I2 = 0% (95% confidence interval (CI): 0, 80) and z = 0.91 (P = 0.36). Horizontal lines, 95% CIs.
