Table 2.
Patient characteristics and outcomes of interest; values presented as mean (SD) or N (%) where indicated.
| Patient characteristics | MPS IA (N = 24) | MPS II (N = 14) | MPS VI (N = 10) |
|---|---|---|---|
| Male | 11 (50.0%) | 14 (100.0%) | 3 (30.0%) |
| Age at first assessment (years) | 15.23 (6.11) | 10.27 (2.79) | 16.06 (5.58) |
| Number of visits | 2.38 (1.10) | 2.93 (0.83) | 2.10 (1.29) |
| Age at first treatment (years) | 8.98 (5.31) | 7.52 (2.97) | 9.76 (4.81) |
| Number of years on treatment (years) | 6.25 (3.39) | 2.75 (1.84) | 6.30 (2.52) |
| Outcomes of interest | |||
| PSS | 8.88 (2.98) | 8.07 (1.44) | 9.60 (2.84) |
| FSIQ | 93.46 (18.43) | 98.21 (15.46) | 96.30 (20.91) |
| TOVA: d prime | 81.91 (14.40) | 81.14 (13.89) | 77.10 (11.06) |
| TOVA: omission errors | 76.77 (25.50) | 76.07 (27.27) | 67.20 (29.20) |
| TOVA: reaction time | 93.64 (21.38) | 87.86 (22.23) | 100 (13.71) |
| TOVA: variability | 83.36 (22.67) | 75.64 (25.21) | 84.40 (21.51) |
Notes: Attenuated MPS I or MPS IA includes both Hurler-Scheie and Scheie patients. 2 MPS IA patients did not have TOVAs; n = 22 for the TOVA in this group.