Table 4.
Predictors of long term mortality in univariate Cox survival analysis
| Variables | HR | 95%CI | P |
| Age (per 1 yr) | 1.02 | 1.01-1.03 | 0.001b |
| HCV (ETOH reference) | 1.45 | 1.03-2.04 | 0.03a |
| Splenectomy (yes) | 3.32 | 1.36-8.10 | 0.008b |
| CHF (yes) | 1.32 | 1.01-1.74 | 0.04a |
| Hypothyroidism (yes) | 1.20 | 1.00-1.42 | 0.04a |
| CKD on HD (yes) | 1.56 | 1.17-2.06 | 0.002b |
| Portal vein pressure before TIPS (per 1 mmHg) | 1.03 | 1.01-1.04 | 0.008b |
| RA pressure before TIPS (per 1 mmHg) | 1.03 | 1.01-1.06 | 0.01a |
| RA pressure after TIPS (per 1 mmHg) | 1.03 | 1.00-1.05 | 0.02a |
| MELD score (per 1 unit) | 1.07 | 1.05-1.09 | < 0.001b |
| Albumin (per 1 mg/dL) | 0.70 | 0.58-0.84 | < 0.001b |
| Billirubin (per 1 mg/dL) | 1.05 | 1.03-1.07 | < 0.001b |
| INR (per 1 unit change) | 1.30 | 1.07-1.60 | 0.01a |
| Creatinine (per 1 mg/dL) | 1.26 | 1.14-1.39 | < 0.001b |
| CTP category B (reference A) | 1.98 | 1.24-3.18 | 0.004b |
| CTP category C (reference A) | 3.02 | 1.85-4.94 | < 0.001b |
| EF echocardiogram pre TIPS (per 1% increase) | 0.98 | 0.95-1.00 | 0.04a |
| RVSP pre TIPS (per 1 mmHg increase) | 1.02 | 1.01-1.04 | 0.005b |
| Moderate RV dysfunction (normal RV reference) | 2.84 | 1.18-6.85 | 0.02a |
| EF post TIPS (per 1% increase) | 0.98 | 0.96-1.00 | 0.03a |
| RVSP post TIPS (per 1 mmHg increment) | 1.02 | 1.01-1.04 | 0.01a |
a
P < 0.05;
b
P < 0.01. CHF: Congestive heart failure; CKD: Chronic kidney disease; CTP: Child turcotte pugh; EF: Ejection fraction; HCV: Hepatitis C virus; HD: Hemodialysis; HR: Hazard ratio; MELD: Model for End stage Liver Disease; RA: Right atrium; RV: Right ventricle; RVSP: Right ventricular systolic pressure; TIPS: Transjugular intrahepatic portosystemic shunt; INR: International normalized ratio; ETOH: Alcoholic etiology.