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. 2016 Apr 15;6:24397. doi: 10.1038/srep24397

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Copyright © 2016, Macmillan Publishers Limited

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(a) IL-6 increases the transcriptional level of IL-6 signaling-related genes in a dose-dependent manner (Single*, double** and triple*** marked represent statistical significance in p < 0.05, p < 0.01 and p < 0.001 in comparison with their control samples, respectively). (b) sgp130 inhibits HepG2 cell growth in a dose-dependent manner as measured with MTT. (c) Apoptosis of HepG2 cells analyzed with FACS after IL-6 or sgp130 treatment for 24 h. (d) Observed with the PI and Annexin-FITC stained HepG2 cells before FACS analysis (red image observed with UV laser; green image observed with blue light).