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. 2016 Apr 15;6:24547. doi: 10.1038/srep24547

Figure 6. The anti-inflammatory effects targeted necroptosis after TBI.

Figure 6

The treatment of hypothermia, DMSO, Nec-1, GSK′ 872 and NSA were performed at 30 minutes after FPI. Rats were sacrificed at 6 h after surgical operation. (A) Cortical expressions of HMGB1, TNF-α, IL-6 and IL-18 were assessed by Western blot analysis. β-actin was used as the loading. (B–E) Quantitative analysis of HMGB1, TNF-α, IL-6 and IL-18 expressions were performed (n = 6 each). Data are expressed as mean ± SD. *p < 0.05, **p < 0.