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. Author manuscript; available in PMC: 2017 Apr 12.
Published in final edited form as: Cell Metab. 2016 Apr 12;23(4):622–634. doi: 10.1016/j.cmet.2016.03.005

Figure 5. ERRγ regulates oxidative capacity through metabolic gene expression inβ-like cells.

Figure 5

(A–C) Relative expression of metabolic (A), KATP channel related (B) and β cell lineage genes (C) in iβLGFP cells, iβeta cells and human islets, as determined by qPCR (n=3). (D) Electron microscopy images showing mitochondrial morphology (left panel) and crystallized insulin granules (right panels) in iβLGFP and iβeta cells, respectively. (E) Oxidative capacity of iβLGFP and iβeta cells, as measured by oxygen consumption rate (OCR). *p<0.05 Student’s unpaired t-test.