Table 2. Percent inhibition of multiple kinases enzymatic activity exhibited by the target compounds (16e, 21b, 21c, 21e) at 10 μM.

Cpd ID	Inhibition % at 10 μM
	VEGFR-2	c-Kit	c-Raf	c-Src	RET
16e	83	72	53	1	84
21b	94	81	35	7	87
21c	96	83	26	8	91
21e	100	64	71	6	91
Staurosporine, 1 μM		93	N/A	98	96
Sorafenib, 1 μM		N/A	92	N/A	N/A