Table 5. Effect of compounds (21b, 2le) and sorafenib on vital organs’ indices of mice with EAC solid tumor.

Groups	Dose (mg/kg/day), po	Liver Index	Kidney Index	Heart Index	Brain Index
Control	--------	0.056 ± 0.01	0.011 ± 0.001	0.0049 ± 0.0009	0.018 ± 0.002
21b	5	0.049 ± 0.01	0.012 ± 0.003	0.0048 ± 0.0014	0.0164 ± 0.004
21b	10	0.051 ± 0.017	0.011 ± 0.003	0.0046 ± 0.0017	0.0167 ± 0.004
21e	5	0.048 ± 0.006	0.012 ± 0.002	0.0044 ± 0.0013	0.0167 ± 0.002
21e	10	0.057 ± 0.007	0.013 ± 0.002	0.0056 ± 0.0009	0.0174 ± 0.002
Sorafenib p-toluenesulfonate	10	0.052 ± 0.005	0.013 ± 0.003	0.0057 ± 0.0009	0.018 ± 0.002

Data are presented as mean ± SD (n = 6).