Figure 6.

Expression of vitamin D system genes and vitamin D target genes in xenografts. mRNA levels were determined by qRT‐PCR as described in the methods section. (a) mRNA expression of the 1,25‐D₃‐degrading enzyme CYP24A1. (b) mRNA expression of the 1,25‐D₃‐activating enzyme CYP27B1. Expression of vitamin D target genes: (c) the calcium channel TRPV6, and (d) prostaglandin E2‐degrading enzyme 15‐PGDH. Patterned bars: diet containing 20% soy. Data were log transformed to achieve normal distribution and statistical analysis was performed using two‐way ANOVA with Tukey's multiple comparison, *p < 0.05, **p < 0.01, ***p < 0.001.