Table 2.

Methylation Frequency of Individual Markers and the Combined Biomarker Panel in Biliary Brush Sample Sets

Samples/Biomarkers	CDO1	CNRIP1	SEPT9	VIM	Biomarker Panel
CCA biliary brush test set (n = 15)	47% (7/15)	67% (10/15)	67% (10/15)	33% (5/15)	73% (11/15)
CCA biliary brush validation set (n = 34)	91% (29/32)	72% (23/32)	53% (17/32)	50% (16/32)	91% (29/32)
CCA biliary brush sample sets combined (n = 49)	77% (36/47)	70% (33/47)	57% (27/47)	45% (21/47)	85% (40/47)
Control/PSC biliary brush sample sets combined (n = 54)	2% (1/50)	0% (0/50)	0% (0/49)	0% (0/50)	2% (1/49)