Table 6.
Summary of upper eyelash characteristics in patients with idiopathic hypotrichosis treated with bimatoprost in treatment period 1 and switched to vehicle in treatment period 2 (intent‐to‐treat population)
| Upper eyelash characteristics/visita | Treatment | Mean ± SD at baseline (mean % change from baseline) | ||
|---|---|---|---|---|
| Length (mm) (n = 60) | Thickness (mm2) (n = 60) | Darkness (intensity units) (n = 60)b | ||
| Baseline | Bimatoprost | 5·7 (0·90) | 0·8 (0·32) | 152·5 (20·05) |
| Month 4 | 6·8 (21·01) | 1·2 (73·70) | 126·3 (−16·01) | |
| Month 6 | 7·1 (25·70) | 1·2 (79·90) | 128·0 (−14·89) | |
| Month 10 | Vehicle | 6·0 (6·46) | 0·8 (13·00) | 143·7 (−3·97) |
| Month 12 | 5·9 (4·62) | 0·9 (15·90) | 143·6 (−4·29) | |
Bimatoprost, bimatoprost ophthalmic solution 0·03%. aVisit was based on visit window. Baseline was defined as the most recent evaluation prior to day 1. Last observation carried forward was performed. bThe scale of intensity units is 0–255, where 0 is black and 255 is white. Therefore, lower values indicate darker eyelash colour and higher values indicate lighter eyelash colour; negative changes from baseline indicate darker eyelashes compared with baseline.