Figure 6.

Convergent gene coexpression modules marking chicken nidopallium and mouse layer IV. We explored which genes are actively transcribed in the regions of controversial ancestry in a representative bird (chicken) and mammal (mouse) at adult stages (Belgard et al., 2013). This study conducted four analyses comparing the expression patterns of their 5,130 most highly expressed one‐to‐one orthologous genes that considered global patterns of expression specificity, strong gene markers, and coexpression networks. Expression correlations between genes in significantly overlapping gene coexpression modules expressed in chicken nidopallium and mouse layer IV (Bonferroni‐corrected P = 4.6 × 10^‐3, hypergeometric test). Nidopallium and neocortical layer IV are generally considered by the community of comparative neurobiologists functionally analogous and hodologically similar to ventral and dorsal pallial derivatives. The nidopallium and layer IV showed weak but significant convergence in gene expression despite their very different developmental trajectories and agrees with previous hodological and functional. Figure modified from Belgard et al. (2013).