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. 2015 Sep 9;36(11):4334–4345. doi: 10.1002/hbm.22921

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© 2015 The Authors. Human Brain Mapping Published by Wiley Periodicals, Inc.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Cortical glutamate/GABA ratios in the child and adult brain per region. ¹H‐MRS voxel (2x2x2cm) positions for (A) inferior frontal gyrus (IFG), (B) intraparietal sulcus (IPS), and (C) inferior occipital gyrus (IOG) are shown on coronal slices. D: Total quantities of the normalized glutamate/GABA ratios in the IFG, IPS, and IOG. Children showed significantly higher relative excitation levels than adults in the IFG. *** P <0.001. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]