Table 1. MLD patient characteristics.

Patient	MLD Subtype	Age (years)	Sex	ARSA (nmol/hr/mg)	Urine Sulfatides (μg/mg creatinine)	MRI	Symptomatic
1	LI	2.3	F	<1% of normal	4	abnormal	yes
2	LJ	11.1	F	1.9	3	abnormal	yes
3	Adult	42.4	M	“10% of normal”	“elevated”	abnormal	yes
4	Adult	44.2	F	21.8	6.6	abnormal	yes
5	Adult	42.5	F	“low”	6.6	abnormal	yes
6	EJ	5.8	F	8.8	5.9	abnormal	yes
7	LJ	19.6	M	4.1	“excessive”	abnormal	yes
8	EJ	4.5	M	“abnormally low*	“great excess”	abnormal	yes

ARSA and urine sulfatide values or comments were taken from the official diagnostic laboratory report. MLD subtypes: late infantile (LI), late juvenile (LJ), early juvenile (EJ), late juvenile (LJ).