Table 2. CSF and plasma cytokine values.
| Cytokine | CSF (pg/mL) |
Plasma (pg/mL) |
|||
|---|---|---|---|---|---|
| MLD | Control | P-value | MLD | Reference | |
| MCP-1 | 987.3 (505.0–1964.0) | 330.7 (153.9–632.6) | 0.0002 | 108.1 (13.0–601.8) | 77.5 (52.7–113.9)* |
| IL-8 | 71.7 (26.3–125) | 13.9 (7.3–24.1) | <0.0001 | 4.4 (1.2–12.2) | 1.35 (0.6–2.8)* |
| VEGF | 1.7 (0.0–4.7) | 0.0 (0.0–0.0) | 0.001 | 23.8 (4.8–122.5) | 28.9 (14.5–57.5)* |
| MIP-1b | 15.1 (0.0–33.7) | 1.7 (0.0–15.6) | 0.003 | n.d. | n.d. |
| IL-1Ra | 51.7 (0.0–136.0) | 7.4 (0.0–76.4) | 0.009 | 1282 (161.3–7285.0) | 169.2 (134.7–203.6)† |
Shown are geometric mean and range for each cytokine.
*Represents data from women aged 18–55 years (geometric mean and 1 standard deviation) reported by Berrahmoune et al.15.
†Represents data from Group age 7–17 years (median and interquartile range) reported by Kleiner et al.16. P-values are derived from a Student’s t-test. Abbreviations: n.d., not done.