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. 2016 Mar 30;15(4):405–419. doi: 10.1111/gbb.12287

Figure 1.

GBB-12287-FIG-0001-c

Conditional Bcl11b mutants exhibit a progressive phenotype at 6 months of age. (a,b) Immunofluorescence staining of 6‐month‐old hippocampal control (a) and conditional Bcl11b mutant (b) sections. (c–h) Cresyl violet staining of plastic sections of control (c,e,g) and conditional Bcl11b mutant (d,f,h) hippocampi. (i,j) Quantitative analysis of the dentate gyrus area (i) and granule cell number (j). (k,l) Quantitative analysis and distribution of BrdU at 4 (4d) and 28 (28d) days after the initial BrdU injection (k) and TUNEL (l), positive cells of control and conditional Bcl11b mutant hippocampi sections. Supra, suprapyramidal blade; Infra, infrapyramidal blade; scale bar, 25 µm (h), 75 µm (b) and 100 µm (d); t‐test, numbers indicate P‐values; error bars, SEM; n = 3 (k; 4 days mutant; 28 days control; l), n = 4 (i–j; k: 4 days control; 28 days mutant).