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Distribution of genetic lesions in different lung carcinoma entities. Mutations in RB1 and TP53 shown in the upper panel. Missense mutations occurring in all four NOTCH genes (NOTCH1‐4) shown in the lower panel. DNA of 19 pulmonary large cell neuroendocrine carcinomas (LCNEC) and 33 pulmonary adenocarcinomas (AdC) was analyzed by NGS. – not expressed; + expressed; ++ strongly expressed; * dot‐like expressed; na – not available.
