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. Author manuscript; available in PMC: 2016 Apr 15.
Published in final edited form as: J Immunol. 2012 Oct 3;189(10):5029–5036. doi: 10.4049/jimmunol.1201892

Table 2.

Correlations between γδ, CD4+ and CD8+ T, and FoxP3+ cell Expression and Clinicopathologic Characteristics in Breast Cancer Patients.

γδ T (n=46) P FoxP3 (n=81) P CD4 (n=81) P CD8 (n=81) P
≤9 >9 ≤12 >12 ≤16 >16 ≤13 >13
Age
<60 years 12 11 23 18 23 18 14 25
≥60 years 11 12 0.878 21 18 0.982 24 15 0.789 21 20 0.247

Tumor stage
I 17 0 24 6 27 3 7 23
II 6 10 18 12 15 15 15 15
III 1 12 1.19×10−6 3 18 1.69×10−5 6 15 2.75×10−5 13 8 0.015

Tumor size
<2.1 cm 15 8 27 14 30 11 15 24
≥2.1 cm 9 14 0.101 17 22 0.075 17 22 0.014 20 21 0.481

Nodal status
Negative 21 4 30 12 32 10 11 31
positive 3 18 9.94×10−6 15 24 0.006 16 23 0.003 24 15 2.84×10−3

ER status
Negative 8 3 12 11 11 12 7 16
Positive 16 19 0.223 33 25 0.890 37 21 0.285 28 30 0.225

HER2
High 2 12 10 12 13 9 11 11
Low 21 7 29 14 28 15 15 28
Negative 2 2 0.002 3 7 0.049 2 8 0.033 6 4 0.249

Relapse-free Survival
No-recurrance 24 8 39 16 38 17 12 35
Recurrence 0 14 1.27×10−5 3 14 3.04×10−4 7 10 0.073 15 19 2.67×10−5

Overall Survival
Alive 24 7 40 16 37 19 17 39
Died 0 15 3.97×10−6 5 20 4.89×10−5 11 14 0.105 18 7 1.14 ×10−3

Note: Evaluated by χ2 test. Abbreviations: ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; FoxP3, forkhead box protein P3.

HHS Vulnerability Disclosure