Table 2.

Pharmacological profiles of 2-phenylcyclopropylmethylamine-based compounds.

Compound	5-HT2C		5-HT2A		5-HT2B		Ref.
	EC50 [nm]	Emax [%]	EC50 [nm]	Emax [%]	EC50 [nm]	Emax [%]
9	2697	109	NA	–	>5000	29	[21]
(±)-10	13	96	1399	74	85	93	[21]
(+)-10 (1S, 2S)	5.2	108	1396	79	37	111	[21]
11	4.8	95	585	86	65	93	[21]
13 (X=F)	21	71	894	28	289	21	[22]
14 (X=OH)	9.3	70	372	18	NA	–	[22]
15 (X=H)	55	61	NA	–	NA	–	[23]
16	4.2	87	374	56	NA	–	[24]
17	3.4	89	359	76	NA	–	[24]

NA: no activity at 10 μm; – not applicable.