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. 2016 Jan 12;127(15):1847–1855. doi: 10.1182/blood-2015-10-677633

Table 1.

Coagulation tests and dp-ucMGP concentration before and after treatment with K vitamins

Baseline After vitamin K1 (10 mg/day)* After vitamin K1 (20 mg/day) Normal values Hemostatic level (%)
Prothrombin activity (%) 11 36 42 70-100
Ratio of APTT 1.65 1.24 1.02 0.84-1.21
Factor II (%) 26 46 38 50-150 20-30
Factor VII (%) <1 21 37 50-150 15-20
Factor IX (%) 12 53 54 50-150 10-40
Factor X (%) 13 27 31 50-150 15-20
Factor V (%) 80 50-150
Protein C (%) 7 13 21 70-140
Protein S (%) 10 6 8 60-120
dp-ucMGP (pM) 2387 2750 2407 32-546
*

Taking daily oral doses of 10 mg of vitamin K1 over 3 months.

Taking daily oral doses of 20 mg of vitamin K1 for more than 1 year, plus taking daily doses of 41 mg of MK-4 and 2 mg of MK-7 over 6 months.

Median value is 172.10