Table 1.
Association between demographic and clinical characteristics to VTE risk in each cohort
| Characteristic | Discovery cohort | Replication cohort | ||||
|---|---|---|---|---|---|---|
| Cases (n = 146) | Controls (n = 432) | P | Cases (n = 94) | Controls (n = 65) | P | |
| Age, y* | 54.9 ± 16.9 | 59.3 ± 10.9 | .004 | 58.6 ± 16.7 | 64.9 ± 16.0 | .02 |
| Height, cm* | 167.3 ± 10.8 | 168.1 ± 9.8 | .61 | 171.8 ± 12.3 | 170.2 ± 10.2 | .41 |
| Weight, kg* | 93.3 ± 28.9 | 87.4 ± 23.4 | .22 | 99.9 ± 33.4 | 100.0 ± 34.1 | .99 |
| West African Ancestry, % | 81 | 80 | .54 | 77 | 76 | .33 |
| Sex, % | ||||||
| Female | 73.3 | 70.4 | .77 | 45.7 | 45.2 | .82 |
| Male | 26.7 | 29.5† | 54.3 | 54.8 | ||
| VTE location in cases, % | ||||||
| DVT | 51 | 47 | ||||
| PE | 2 | 36 | ||||
| DVT/PE | 24 | 17 | ||||
*
Values are mean ± standard deviation.
†
Association between sex and risk of VTE excluded DCPC controls.