Fig. 6.

The effect of BH3 mimetic combinations on annexin V/propidium iodide staining. Ovcar-8 cells were exposed to 66 μM carboplatin or the indicated BH3 mimetic (at the concentration indicated in the Methods section) for 48 h, the cells were labelled with annexin V and propidium iodide and assessed by flow cytometery. The results shown are representative of 3 experiments. The results with other cell lines are summarized in Table 2