Table 1.
Estimated doses administered to Lister Hooded rats
| Low dose treatment regimen |
High dose treatment regimen |
||
|---|---|---|---|
| Rat number | Estimated dose (mg/kg/day) | Rat number | Estimated dose (mg/kg/day) |
| H206 | 13.17 | B426 | 106.80 |
| I206 | 16.00 | D426 | 102.17 |
| K206 | 11.16 | H426 | 100.15 |
| M206 | 18.33 | K426 | 134.35 |
| R206 | 18.16 | L426 | 136.76 |
| T206 | 22.50 | M426 | 135.26 |
| V206 | NM | N426 | 112.27 |
| W206 | 16.17 | O426 | 118.75 |
| U351 | 20.24 | R426 | 129.37 |
| V351 | 27.98 | S426 | 114.60 |
| AC351 | 14.13 | V426 | 105.92 |
| V654 | NM | W426 | 81.00 |
| W654 | NM | Y426 | 112.15 |
| K207 | 18.90 | AA426 | 112.13 |
| P214 | 13.08 | AC426 | 115.61 |
| A233 | 12.32 | C426 | 161.05 |
| B233 | 11.07 | I426 | 65.43 |
| C233 | 9.57 | U426 | 82.32 |
| D233 | 13.70 | ||
| D250 | 14.50 | ||
| F250 | 12.43 | ||
| F233 | NM | ||
| A250 | 11.10 | ||
| E250 | NM | ||
| E233 | 22.50 | ||
| I250 | 16.13 | ||
| C250 | 14.58 | ||
| L250 | NM | ||
| H250 | NM | ||
| J250 | NM | ||
| K250 | NM | ||
| B250 | 16.75 | ||
| G250 | 12.42 | ||
| M184 | 11.92 | ||
| R184 | 10.42 | ||
| Mean | 15.36 | Mean | 112.56 |
| SD | 4.40 | SD | 22.66 |
The low and high dose regimens are reported separately, with the respective mean values. Dose was estimated by assuming 300 g for rat body weight.
NM, not measured.