Table 2.
Exposure data from rats treated at low dose treatment regimen. Results obtained from black and white fur are reported separately
Dose* | Exposure (black fur) |
Exposure (white fur) | |||
---|---|---|---|---|---|
Rat number | mg/kg/day (mean) | Cocaine (ng/mg) | BE (ng/mg) | Cocaine (ng/mg) | BE (ng/mg) |
W654 | 20.66 | 4.008 | 1.086 | 0.231 | 0.508 |
V654 | 26.84 | 0.474 | 0.481 | Out | Out |
K207 | 18.90 | 0.982 | 0.375 | 0.218 | 0.360 |
P214 | 13.08 | 0.534 | 0.287 | 0.290 | 0.334 |
R206 | 18.16 | 3.446 | 0.951 | 0.160 | 0.313 |
T206 | 22.50 | 0.833 | 0.437 | 0.187 | 0.480 |
K206 | 11.16 | 1.280 | 0.380 | 0.108 | 0.259 |
M206 | 18.33 | 0.648 | 0.303 | 0.152 | 0.305 |
H206 | 13.17 | 1.139 | 0.398 | 0.129 | 0.671 |
I206 | 16.00 | 0.645 | 0.232 | 0.172 | 0.954 |
W206 | 16.17 | Out | Out | 0.218 | 0.393 |
Mean | 17.72 | 1.399 | 0.493 | 0.186 | 0.458 |
SD | 4.55 | 1.261 | 0.288 | 0.054 | 0.213 |
Ecgonine methylester is not reported, as not measurable in most of the samples.
*Assuming 300 g of rat body weight.
BE, benzoylecgonine; Out, outlier.