Table 4.

Summary of heart weight data

Rat code	Treatment duration (self-administration)	Cocaine estimated dose (mg/kg/day)	Body weight (g)	Heart weight (g)	Brain weight	Heart to body ratio	Heart to brain ratio	ANP (pg/mL)
M184	4 months	15.4	320	1.178	NM	0.368	–	9101.50
R184	4 months	15.4	305	1.081	NM	0.354	–	11 853.38
A233	3 months	15.4	360	1.085	NM	0.301	–	10 175.46
B233	3 months	15.4	320	1.095	NM	0.342	–	10 748.12
C233	3 months	15.4	348	1.073	NM	0.308	–	6231.20
D233	3 months	15.4	335	1.260	NM	0.376	–	19 779.27
A250	3 months	15.4	340	1.095	NM	0.322	–	NM
D250	3 months	15.4	360	1.050	NM	0.292	–	5046.99
F250	3 months	15.4	355	1.004	NM	0.283	–	4238.72
I184	4 months	0 (Saline control)	300	1.086		0.362		NM
V654	35 days	15.4	NM	0.957	NM	–	–	NM
W654	35 days	15.4	NM	0.913	NM	–	–	NM
K207	35 days	15.4	NM	0.937	NM	–	–	NM
P214	35 days	15.4	NM	0.966	NM	–	–	NM
A426	31 days	0 (Saline control)	318	0.930	1.66	0.292	56.02	6386.06
C426	2 weeks	112.6	315	1.080	1.75	0.343	61.71	18 800.68
G426	31 days	0 (Saline control)	327	0.930	1.76	0.284	52.84	7243.34
I426	2 weeks	112.6	249	0.880	1.71	0.353	51.46	17 559.12
L426	31 days	112.6	312	0.940	1.66	0.301	56.63	6609.90
M426	31 days	112.6	288	1.230	1.5	0.427	82.00	6151.69
O426	31 days	112.6	326	0.960	1.7	0.294	56.47	6997.02
U426	2 weeks	112.6	302	1.100	1.63	0.364	67.48	25 211.15
V426	31 days	112.6	307	0.920	1.77	0.300	51.98	7186.62
Mean values per dose: 0 mg/kg/day			315.0	0.982	1.710	0.313	54.433	6814.70
15.4 mg/kg/day			338.1	1.053		0.327		9646.83
112.6 mg/kg/day			299.9	1.016	1.674	0.340	61.105	12 645.17

A comparison with treatment type, dose and ANP values is also included. A colour code was associated with the estimated dose: white for saline controls, light grey for low dose and dark grey for high dose.

ANP, atrial natriuretic peptide; NM, not measured.