Table 4. Mitochondrial proteins detected and changed by Palmfeld functional subcategories [28].
Protein category | proteins | detected | changed | % detected | % significant |
---|---|---|---|---|---|
Citric acid cycle | 30 | 25 | 6 | 83% | 24% |
Mitochondrial morphology | 12 | 6 | 1 | 50% | 17% |
Mitochondrial translation | 99 | 44 | 7 | 44% | 16% |
Antioxidant systems | 33 | 17 | 2 | 52% | 12% |
Respiratory chain | 82 | 58 | 5 | 71% | 9% |
Amino acid metabolism | 64 | 35 | 3 | 55% | 9% |
Fatty acid metabolism | 21 | 18 | 1 | 86% | 6% |
Protein quality control systems | 16 | 12 | 0 | 75% | 0% |
Apoptosis | 7 | 3 | 0 | 43% | 0% |
Known disease association (OMIM database) | 36 | 31 | 5 | 86% | 16% |