Table 6.
Significant cytoskeletal protein changes (p<0.05 or exclusively in one group).
| Uniprot # | Gene Name | p-value | fold | Description |
|---|---|---|---|---|
| P10922 | H1f0 | ↑ | Histone H1.0 | |
| Q9EPR4 | Slc23a2 | ↑ | Solute carrier family 23 member 2 | |
| Q8BTY2 | Slc4a7 | 0.006 | 2.84 | Sodium bicarbonate cotransporter 3 |
| P14115 | Rpl27a | 0.002 | 2.77 | 60S ribosomal protein L27a |
| Q8BIW1 | Prune | 0.031 | 2.71 | Protein prune homolog |
| Q8R5J9 | Arl6ip5 | 0.043 | 2.63 | PRA1 family protein 3 |
| Q9D8E6 | Rpl4 | 0.003 | 2.58 | 60S ribosomal protein L4 |
| P54285 | Cacnb1 | 0.021 | 2.15 | Voltage-dependent L-type calcium channel subunit beta-1 |
| P63001 | Rac1 | 0.029 | 2.02 | Ras-related C3 botulinum toxin substrate 1 |
| Q60668 | Hnrnpd | 0.036 | 1.91 | Heterogeneous nuclear ribonucleoprotein D0 |
| Q9JKK7 | Tmod2 | 0.015 | 1.91 | Tropomodulin-2 |
| P14206 | Rpsa | 0.048 | 1.83 | 40S ribosomal protein SA |
| Q9ERD7 | Tubb3 | 0.043 | 1.80 | Tubulin beta-3 chain |
| Q3V0K9 | Pls1 | 0.032 | 1.80 | Plastin-1 |
| Q8CHH9 | sept8 | 0.046 | 1.66 | Septin-8 |
| Q9CPR4 | Rpl17 | 0.020 | 1.55 | 60S ribosomal protein L17 |
| P19246 | Nefh | 0.021 | 1.38 | Neurofilament heavy polypeptide |
| Q9ERS2 | Ndufa13 | 0.034 | -1.49 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 |
| P54227 | Stmn1 | 0.040 | -1.81 | Stathmin |
| Q4KMM3 | Oxr1 | 0.019 | -1.87 | Oxidation resistance protein 1 |
| Q9CPW4 | Arpc5 | 0.044 | -1.90 | Actin-related protein 2/3 complex subunit 5 |
| O08788 | Dctn1 | 0.042 | -1.98 | Dynactin subunit 1 |
| P70336 | Rock2 | 0.014 | -2.22 | Rho-associated protein kinase 2 |
| O54962 | Banf1 | 0.023 | -2.42 | Barrier-to-autointegration factor |
| Q0GNC1 | Inf2 | 0.004 | -2.45 | Inverted formin-2 |
| P62627 | Dynlrb1 | 0.030 | -2.45 | Dynein light chain roadblock-type 1 |
| Q58A65 | Spag9 | 0.022 | -2.46 | C-jun-amino-terminal kinase-interacting protein 4 |
| Q9Z2H5 | Epb41l1 | 0.027 | -2.53 | Band 4.1-like protein 1 |
| Q9CQI3 | Gmfb | 0.017 | -2.57 | Glia maturation factor beta |
| Q811D0 | Dlg1 | 0.044 | -2.69 | Disks large homolog 1 |
| Q91VR8 | Brick1 | 0.030 | -2.70 | Probable protein BRICK1 |
| P27546 | Map4 | 0.018 | -2.80 | Microtubule-associated protein 4 |
| Q9CQX8 | Mrps36 | 0.028 | -3.13 | 28S ribosomal protein S36, mitochondrial |
| P23116 | Eif3a | 0.012 | -3.38 | Eukaryotic translation initiation factor 3 subunit A |
| Q61301 | Ctnna2 | 0.048 | -3.44 | Catenin alpha-2 |
| P28740 | Kif2a | 0.011 | -3.52 | Kinesin-like protein KIF2A |
| P21619 | Lmnb2 | 0.041 | -3.60 | Lamin-B2 |
| Q8BRT1 | Clasp2 | 0.016 | -3.67 | CLIP-associating protein 2 |
| Q9QYB5 | Add3 | 0.026 | -3.72 | Gamma-adducin |
| Q9QWI6 | P140 | 0.017 | -3.89 | p130Cas-associated protein |
| O70161 | Pip5k1c | 0.016 | -3.93 | Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma |
| Q9JMH9 | Myo18a | 0.023 | -4.30 | Myosin-XVIIIa |
| Q9DBR7 | Ppp1r12a | 0.009 | -4.79 | Protein phosphatase 1 regulatory subunit 12A |
| Q9QXL2 | Kif21a | 0.022 | -5.61 | Kinesin-like protein KIF21A |
| Q4ACU6 | Shank3 | 0.012 | -5.85 | SH3 and multiple ankyrin repeat domains protein 3 |
| Q6P9K8 | Caskin1 | 0.042 | -6.95 | Caskin-1 |
| Q7TMB8 | Cyfip1 | 0.001 | -7.32 | Cytoplasmic FMR1-interacting protein 1 |
| Q80U40 | Rimbp2 | 0.015 | -7.67 | RIMS-binding protein 2 |
| Q3UHD9 | Agap2 | <0.000003 | -11.45 | Arf-GAP, GTPase, ANK repeat and PH domain-containing protein 2 |
| P08556 | Nras | ↓ | GTPase NRas | |
| Q9QWY8 | Asap1 | ↓ | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 | |
| P58059 | Mrps21 | ↓ | 28S ribosomal protein S21, mitochondrial | |
| Q03173 | Enah | ↓ | Protein enabled homolog | |
| Q6PFD5 | Dlgap3 | ↓ | Disks large-associated protein 3 | |
| Q923D5 | Wbp11 | ↓ | WW domain-binding protein 11 | |
| Q80U49 | Kiaa0284 | ↓ | Protein KIAA0284 | |
| Q6A065 | Cep170 | ↓ | Centrosomal protein of 170 kDa | |
| Q6PDI5 | Ecm29 | ↓ | Proteasome-associated protein ECM29 homolog | |
| Q8C1B1 | Camsap1l1 | ↓ | Calmodulin-regulated spectrin-associated protein 1-like protein 1 | |
| P39054 | Dnm2 | ↓ | Dynamin-2 | |
| Q3UH68 | Limch1 | ↓ | LIM and calponin homology domains-containing protein 1 | |
| Q3UU96 | Cdc42bpa | ↓ | Serine/threonine-protein kinase MRCK alpha | |
| Q7SIG6 | Asap2 | ↓ | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 | |
| Q810B6 | Ankfy1 | ↓ | Ankyrin repeat and FYVE domain-containing protein 1 | |
| Q8BPM0 | Daam1 | ↓ | Disheveled-associated activator of morphogenesis 1 | |
| Q9JL26 | Fmnl1 | ↓ | Formin-like protein 1 |