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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Mol Genet Metab. 2016 Mar 7;118(1):41–54. doi: 10.1016/j.ymgme.2016.03.003

Table 8. Shared transcriptomic and proteomic terms grouped by assigned functional category.

Immune Mitochondria
GO:0001775-cell activation GO:0005739-mitochondrion
GO:0002252-immune effector process GO:0031090-organelle membrane
GO:0002443-leukocyte mediated immunity GO:0055114-oxidation reduction
GO:0002684-positive regulation of immune system process Development

GO:0006955-immune response GO:0035239-tube morphogenesis
GO:0007186-G-protein coupled receptor protein signaling pathway GO:0035295-tube development
GO:0010033-response to organic substance nucleus
GO:0016192-vesicle-mediated transport GO:0000166-nucleotide binding
GO:0045321-leukocyte activation Transcription

IPR013783:Immunoglobulin-like fold GO:0045449-regulation of transcription
transducer Transport

Vesicle transport

cytoplasmic vesicle Not assigned

GO:0006897-endocytosis acetylation
GO:0010324-membrane invagination alternative splicing
GO:0016023-cytoplasmic membrane-bounded vesicle cell membrane
GO:0016044-membrane organization cytoplasm
GO:0031410-cytoplasmic vesicle disulfide bond
GO:0031982-vesicle glycoprotein
GO:0031988-membrane-bounded vesicle glycosylation site:N-linked (GlcNAc…)
GO:0051130-positive regulation of cellular component organization GO:0000267-cell fraction
mmu04142:Lysosome GO:0005506-iron ion binding
Extracellular matrix/Adhesion GO:0005615-extracellular space

cell adhesion GO:0005624-membrane fraction
GO:0005576-extracellular region GO:0005626-insoluble fraction
GO:0007155-cell adhesion GO:0005783-endoplasmic reticulum
GO:0022610-biological adhesion GO:0005886-plasma membrane
GO:0044421-extracellular region part GO:0006355-regulation of transcription, DNA-dependent
Secreted GO:0007166-cell surface receptor linked signal transduction
Apoptosis GO:0007242-intracellular signaling cascade

GO:0008219-cell death GO:0008270-zinc ion binding
GO:0010941-regulation of cell death GO:0008283-cell proliferation
GO:0016265-death GO:0010604-positive regulation of macromolecule metabolic process
GO:0042981-regulation of apoptosis GO:0016021-integral to membrane
GO:0043067-regulation of programmed cell death GO:0031224-intrinsic to membrane
Metabolism GO:0042127-regulation of cell proliferation

GO:0006508-proteolysis GO:0042470-melanosome
GO:0008233-peptidase activity GO:0043167-ion binding
GO:0008234-cysteine-type peptidase activity GO:0043169-cation binding
GO:0070011-peptidase activity, acting on L-amino acid peptides GO:0044459-plasma membrane part
Protease GO:0046872-metal ion binding
Signaling GO:0046914-transition metal ion binding

GO:0019220-regulation of phosphate metabolic process GO:0048770-pigment granule
GO:0042325-regulation of phosphorylation GO:0051252-regulation of RNA metabolic process
GO:0044093-positive regulation of molecular function hydrolase
GO:0051174-regulation of phosphorus metabolic process lipoprotein
Ion transport/Channels membrane

calcium metal-binding
GO:0005509-calcium ion binding mmu04062:Chemokine signaling pathway
GO:0042592-homeostatic process mmu04670:Leukocyte transendothelial migration
GO:0048878-chemical homeostasis mutagenesis site
Neuron oxidoreductase

GO:0007610-behavior phosphoprotein
GO:0030030-cell projection organization receptor
GO:0030182-neuron differentiation sequence variant
GO:0050877-neurological system process signal
Cytoskeleton signal peptide

GO:0005856-cytoskeleton splice variant
GO:0043228-non-membrane-bounded organelle topological domain:Cytoplasmic
GO:0043232-intracellular non-membrane-bounded organelle topological domain:Extracellular
transmembrane
transmembrane region zinc