Table 2.
The rate of decline in renal function (95% CI)
| CKD III–V (n = 2466) | CKD III (n = 618) | CKD IV (n = 1507) | CKD V (n = 341) |
||
|---|---|---|---|---|---|
| Mean declinea | −1.48 (−1.65; −1.31) | −1.52 (−1.96; −1.08) | −1.52 (−1.72; −1.32) | −1.19 (−1.75; −0.64) | |
| Change in eGFR decline per mg/dL increase in UA at baseline (negative = extra decline)a | |||||
| Crude | 0.08 (−0.01; 0.17) | −0.09 (−0.31; 0.12) | 0.14 (0.03; 0.26) | 0.10 (−0.17; 0.37) | 0.20* |
| Adjustedb | 0.09 (−0.01; 0.19) | −0.09 (−0.30; 0.13) | 0.16 (0.04; 0.28) | 0.18 (−0.09; 0.45) | 0.12 |
aIn mL/min/1.73 m2 per year.
bAdjusted for age, sex, PRD, BMI, MAP, protein-restricted diet, diuretics use, statin use and UA-lowering medication use, diabetes, arrhythmia, dementia, CVD, IHD, hypertension, pulmonary disease and CHF.
*P-value for difference in the change in the rate of renal function decline between CKD stages.