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. Author manuscript; available in PMC: 2017 Feb 27.
Published in final edited form as: J Mol Biol. 2016 Feb 17;428(5 Pt A):748–757. doi: 10.1016/j.jmb.2015.11.013

Figure 1. Tools used by Eterna community to assess difficulty of RNA secondary structure design puzzles.

Figure 1

[A] The puzzlemaker interface allows players to define a secondary structure string or insert bases or base pairs at specified positions and then deploy these puzzles to other players to solve. [B] The puzzle solver interface enables players to select nucleotides and paint them over the structure, which can switch between natural and target modes. [C] After puzzle design, players are able to see which bots are able to solve their puzzles. [D] The Eternascript interface allows for players to create and test their own puzzle solving algorithms.