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. 2014 Oct 2;141(2):365–376. doi: 10.1093/toxsci/kfu129

FIG. 7.

FIG. 7.

Predicted (median, thick, solid; 2.5 percentile, lower thin, solid; 97.5 percentile, upper thin, solid) versus observed amounts (×) of Cd in whole blood (A), total plasma (B), kidney (C), and 24-h urine (D). The percentiles were obtained by Monte Carlo simulation using randomly drawn records from all the 82 kidney donors and posterior distributions obtained in the MCMC analysis with Model 1. Also shown are the corresponding predicted amounts (median, thin, dashed) when all parameters were kept fixed to their original K&N values in the MCMC analysis and only the posteriors for the daily systemic uptake, IBW, and the daily uptake from smoking, ISM, were estimated. The number of observations falling above the 97.5 percentiles or below the 2.5 percentiles is also indicated.