TABLE 2. Time-Averaged Normalized Sensitivity Coefficients of Model Parameters for Observed Amounts of Cd.

Parameter	y1 (%)	y2 (%)	y3 (%)	y4 (%)	Average (%)a
IBWb	100	100	99	100	100
C7b	−31	−11	45	43	32
C17b	2.2	1.8	100	−24	32
CX	91	−1.9	7.8	7.7	27
C11	−40	−34	−15	−17	26
C20b	4.0	100	0	0	26
C16b	−95	0.012	0.056	0.045	24
C12	−32	−18	18	20	22
C19b	−1.2	−1.0	−59	18	20
C9	−21	−18	−11	−11	15
C10	17	14	6.9	7.4	11
C14	−1.3	3.4	16	16	9.1
C15	−0.74	−2.2	−4.9	−5.6	3.3
C21	−0.14	−0.12	−7.5	4.8	3.1
C18	2.1	1.8	−3.5	−2.6	2.5
C13	3.2	1.8	−1.7	−1.9	2.1

Abbreviations: y₁, amount in whole blood; y₂, amount in total plasma; y₃, amount in kidney; y₄, amount in 24-h urine; I_BW, BW-dependent daily systemic uptake; C₇, fraction from daily systemic uptake to plasma metallothionein; C₉, fraction from other plasma to other tissue; C₁₀, transfer rate from other tissue to other plasma; C₁₁, fraction from other plasma to fecal excretion; C₁₂, fraction from other plasma to liver; C₁₃, transfer rate from liver to other plasma; C₁₄, transfer rate from liver to plasma metallothionein; C₁₅, excretion rate from liver to feces; C₁₆, transfer rate from red blood cells to plasma metallothionein; C₁₇, tubular reabsorptive capacity; C₁₈, transfer rate from kidney to other plasma; C₁₉, excretion rate of Cd accumulated in kidney to 24-h urine; C_X, fraction from other plasma to red blood cells; C₂₀, fraction of Cd in the plasma compartments contributing to whole blood; C₂₁, decrease in C₁₉.

^aAverage of the absolute values of the sensitivity coefficients.

^bParameter used in MCMC analysis.