FIG. 8.
Radiochromatograms of rat (A), dog (B), and human (C) hepatocytes after incubation for 13 h with 50μM [14C]-labeled compound 1. Peaks 1, 2, and 3 correspond to the parent drug (compound 1), the carboxylic acid (compound 2), and the β-hydroxylated metabolite (compound 3), respectively. The radiochromatograms are displayed on the same intensity scale with parent drug as saturated peak.
