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. 2014 Oct 2;141(2):353–364. doi: 10.1093/toxsci/kfu131

FIG. 8.

FIG. 8.

Radiochromatograms of rat (A), dog (B), and human (C) hepatocytes after incubation for 13 h with 50μM [14C]-labeled compound 1. Peaks 1, 2, and 3 correspond to the parent drug (compound 1), the carboxylic acid (compound 2), and the β-hydroxylated metabolite (compound 3), respectively. The radiochromatograms are displayed on the same intensity scale with parent drug as saturated peak.