TABLE 2. Results for Compounds Tested in the CEGAa.
CEGA | |||
---|---|---|---|
Compound (lowest positive dose/egg) | Comet b | NPL c | |
NP1 (enrichment) | HLB (enrichment) | ||
2-acetylaminofluorene (0.1 mg/egg) | + | + | + |
Fluorene (none) | − | − | − |
Aflatoxin B1 (0.4 μg/egg) | + | − | − |
Aflatoxin B2 (3.2 μg/egg) | ± | − | − |
Benzo[a]pyrene (125 μg/egg) | + | + | + |
Benzo[e]pyrene (none) | − | − | − |
Diethylnitrosamine (0.5 mg/egg) | + | − | − |
Nitrosodiethanolamine (none) | − | − | − |
aEggs were injected three times at 48, 24, and 3 h before termination on day 11 of incubation.
bPositive 1.7-fold control value with dose response.
cPositive at more than one dose; +, positive; –, negative; ±, weakly positive.