Table 1. Life expectancies of mice subjected to caloric restriction and/or genetic disruption of growth hormone signaling.

Caloric restriction	−	+	−	+
Disruption of growth hormone signaling	−	−	+	+
Population A
Number of mice	41	43	38	39
Median life expectancy	903	1127	1181	1188
Increase in median life expectancy	Ref.	25%	31%	32%
Maximal life expectancy	1275	1395	1379	1462
Increase in maximal life expectancy	Ref.	9%	8%	15%
Population B
Number of mice	108	105	97	102
Median life expectancy	634	794	931	1056
Increase in median life expectancy	Ref.	25%	47%	67%
Maximal life expectancy	1171	1307	1308	1537
Increase in maximal life expectancy	Ref.	12%	12%	31%

Median and maximal life expectancies are given in days. Increases in median and maximal life expectancies are given relative to the mice not subjected to caloric restriction or disruption of growth hormone signaling (Ref.).