Table 4.

Analysis of variance on the effect of renal impairment on pharmacokinetic parameters of pridopidine

		Point estimate	90% confidence interval	P value
Mild/normal	C max after single dose	1.06	0.85, 1.31	0.653
	AUC(0,∞) after single dose	0.99	0.69, 1.43	0.977
	C max,ss at steady‐state	0.86	0.69, 1.06	0.222
	AUC(0,τss) at steady‐state	1.06	0.82, 1.37	0.671
Moderate/normal	C max after single dose	0.90	0.80, 1.01	0.121
	AUC(0,∞) after single dose	1.39	1.01, 1.92	0.092
	C max,ss at steady‐state	1.26	1.02, 1.56	0.071
	AUC(0,τss) at steady‐state	1.68	1.22, 2.30	0.014