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The mean plasma concentration‐time profiles of ibrutinib following (n=8) A. Oral administration of 560 mg ibrutinib under fasted ( 
Treatment A) and fed ( 
Treatment B) conditions, and 140 mg ibrutinib under fed condition with grapefruit juice ( 
Treatment C). B. Ibrutinib following oral administration of 560 mg ibrutinib without grapefruit juice ( 
Treatment B) and dose‐normalized ibrutinib with grapefruit juice ( 
Treatment C).
