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Treatment schedule for doxorubicin and trastuzumab to evaluate the order of combination dosing: Experiment 4
| Groups |
Treatments with dosing schedule (days) |
|||
|---|---|---|---|---|
| Group number (N) | Dosing | Doxorubicin | Trastuzumab | Saline |
| 1 (N = 7) | Control | – | – | 0, 3, 4 |
| 2 (N = 7) | Doxorubicin | 4 | – | 0, 3 |
| 3 (N = 7) | Trastuzumab | – | 0, 3 | 4 |
| 4 (N = 7) | Doxorubicin 24 h prior to Trastuzumab | 0 | 1, 4 | – |
| 5 (N = 7) | Trastuzumab 24 h prior to Doxorubicin | 4 | 0, 3 | – |
| 6 (N = 7) | Trastuzumab + Doxorubicin | 0, 3 | 0, 3 | – |
